WebThe overarching goal of this dissertation is to import nucleus-encoded ATP6 protein into the mitochondria.This work examines the efficacies of multiple strategies in enhancing the functional outcomes of the first animal model with a stable and endogenous ATP6 mutation and shows that algal ATP6 protein provides the most promising rescue results. WebAug 21, 2024 · Ubiquitous 4e-bp knockdown using the daughterless-GAL4 promoter reduced 4e-bp transcript levels (Fig. S2A) and also enhanced the effect of cold on survival (Fig. 2 B and C), although a more dramatic temperature challenge (from 18 to 29 °C) was required to reveal the phenotype, possibly due to RNAi affecting 4E-BP levels more …
Arf-GEF localization and function at myosin-rich adherens …
http://d-scholarship.pitt.edu/20724/1/ChiuWK_ETD_Final.pdf WebJul 17, 2024 · Also a dilp2-Gal4 is able to induce DILP8 immunolabeling in IPCs (Supplementary Figure 5F). We also used gene-switch Gal4 drivers (Elav GS and daughterless GS-Gal4), where the Gal4 is activated by feeding the flies RU486 (mifepristone), to switch on DILP8 in neurons of the adult fly (Supplementary Figures … shell house brisbane
The F-box protein Bard (CG14317) targets the Smaug RNA …
WebPubMed Central (PMC) WebApr 1, 2010 · Second, we used a patchy Daughterless Gal4 driver to label a subset of epithelial cells with GFP:Moe (Fig. 1L-L″). In both experiments, similar apical, intermediate and basal-level protrusions rich in actin filaments were evident in labelled cells irrespective of the GFP fusion protein used (GFP:Moe, Pon:GFP, PA-GFP:Moe), the level of ... WebPhosphorylation of eukaryotic translation initiation factor 2 alpha (eIF2α) by the kinase GCN2 attenuates protein synthesis during amino acid starvation in yeast, while in mammals a family of related eIF2α kinases regulate translation in response to shell house bistro