WebApr 10, 2024 · The PATHWAY anti-HER2 (4B5) test now includes a scoring algorithm that helps pathologists to identify “low expressors” of HER2, assigning a HER2 low status to this group of patients. With this lower cutoff, the test is able to identify patients who may benefit from Enhertu as a treatment option. WebApr 13, 2024 · DESTINY-Breast04是一项针对HER2-low、转移性乳腺癌患者(既往接受过一线或二线化疗,以及至少一线内分泌治疗)的3期试验,患者以2:1的比例随机接受德曲 …
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WebDec 10, 2024 · These include DESTINY-Breast02, which is evaluating Enhertu as a 3rd-line treatment for patients with HER2-positive metastatic breast cancer and DESTINY-Breast03, which is testing Enhertu as a 2nd-line treatment for these patients. DESTINY-Breast04 is investigating Enhertu in patients with metastatic breast cancer and low expression of … WebJul 6, 2024 · In the DESTINY-Breast04 trial, the results of which were published in The NEJM last month, patients with HER2-low metastatic breast cancer who had received one or two lines of chemotherapy previously were given trastuzumab deruxtecan. cost flaming grill 293 ferry street buffet
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WebJul 13, 2024 · The currently recruiting phase III DESTINY-Breast04 trial (ClinicalTrials.gov identifier: NCT03734029) that investigates the efficacy of T-DXd in patients with … WebFeb 21, 2024 · DESTINY-Breast04 is the first ever phase 3 trial of a HER2 directed therapy in patients with HER2 low metastatic breast cancer to show a statistically significant and clinically meaningful benefit in [PFS] and overall survival compared to standard treatment,” Ken Takeshita, MD, global head of R&Dat Daiichi Sankyo, said in a press release. WebJan 25, 2024 · Trastuzumab Deruxtecan Stands Out for HER2+ and HER2-Low Breast Cancer Jan 25, 2024 Jessica Hergert Aditya Bardia, MD, MPH, discusses the clinical implications of the DESTINY-Breast03... cost flash drive