Web22 okt. 2024 · MALAT1 has previously been described as a metastasis-promoting long noncoding RNA (lncRNA). We show here, however, that targeted inactivation of the Malat1 gene in a transgenic mouse model of ... Web17 mei 2024 · It has also been described for astrocytes in the context of brain injury, which is frequently characterized by glial scarring: presence of high numbers of reactive …
Spatial and temporal heterogeneity of mouse and human ... - Nature
Web15 mrt. 2024 · MALAT1 downregulation by specific siRNAs enhanced the polarization of macrophages towards the M1 phenotype. ... Gfap (astrocyte marker) and f4/80 (monocytoid cell marker) at the peak and post-peak phases of disease, compared with control animals' spinal cords (Ghorbani et al., 2024; Talebi et al., 2024). WebMALAT1 was identified in multiple types of physiological processes, such as alternative splicing, nuclear organization, epigenetic modulating of gene expression, and a number of evidences indicate that MALAT1 also closely relate to various pathological processes, ranging from diabetes complications to cancers. tje weatjer cjamme om la islasomg pm
ALDH1A1 is a marker of astrocytic differentiation during brain
Web1 mei 2024 · LncRNA MALAT1, also called nuclear-enriched abundant transcript 2, is overexpressed in tumor tissues and correlates with prognosis for many tumors, including non-small cell lung cancer,... Web15 okt. 2024 · The protein levels of HMGB1 significantly decreased ( P = 0.004) in the astrocytic exosomes after 3 days of siRNA treatment ( Fig. 2 C), and the upregulation of … Web21 mrt. 2024 · MALAT1 (Metastasis Associated Lung Adenocarcinoma Transcript 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with MALAT1 … t jet ski